MBC.G2
Biochemistry I
MBC.G2
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Module description |
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Module coordinator |
PD Dr. Helmut Pospiech |
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Requirements for module admission |
None |
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Module is required for |
Specialization module, project module, Master thesis project |
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Type of module |
Basic module, compulsory |
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Frequency of offer (module cycle) |
Yearly |
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Duration of module |
1 Semester (WS) |
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Composition of module / types of components (lecture, exercise, seminar, practical training, excursion) |
Lecture: 7 hours per week per semester |
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Credit points (ECTS credits) |
10 cp |
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Work load in hours:
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105 h 195 h |
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Contents |
This module imparts basic concepts of regulatory aspects of biochemistry. Using examples from primary human metabolism, the student will learn how metabolic flows are regulated in the cell with the help of allosteric effectors, covalent modifications, gene expression and protein stability. This knowledge will then be applied to understand transcriptional regulation, cell growth and division as well as cellular regulatory networks and cross-talk between tissues and organs. The module deals further with the structure and function of nucleic acids: large and small ribozymes, cis- and trans-splicing as well as RNA editing in eukaryotes, regulatory RNAs in pro- and eukaryotes (such as cis- und trans-coded antisense RNAs, micro- and siRNAs), RNA degradation and RNA transport. The module will introduce contemporary methodologies and technologies including sequencing, expression analysis, analysis of protein structure, function and interactions as well as cell and animal model systems. |
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Learning and qualification objectives |
Based on the understanding of fundamental metabolic and biochemical processes in the cells, this module will provide the knowledge how these processes are intertwined within a cell and between different tissues. It thus mediates a comprehensive biochemical view on cellular function and regulation, and introduces modern methods to study cellular functions at a molecular level. The module is organised in three lecture courses. Since many of the topics of this module are not covered by text books, regular participation in the courses is strongly recommended. |
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Requirements for admission to module exam |
None |
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Requirements for the award of credit points; exams (weighting of grades in %) |
Written exams on lectures "Regulatory Aspects of Biochemistry" (40%), "Basics of Analytical Biochemistry" (30%) |