MBC.A4
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Module description |
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Module coordinator |
Prof. Dr. Berit Jungnickel |
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Requirements for module admission |
Enrolment in one basic module |
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Module is required for |
Specialization module |
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Type of module |
Required elective module, advanced module |
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Frequency of offer (module cycle) |
Yearly |
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Duration of module |
1 Semester (SS) |
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Composition of module / types of components (lecture, exercise, seminar, practical training, excursion) |
Lecture: 2 hours per week per semester Practical training/exercise: 4 hours per week per semester Seminar: 1 hour per week per semester |
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Credit points (ECTS credits) |
10 cp |
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Work load in hours:
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105 h 195 h |
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Contents |
The lecture deals with causes and consequences of genomic instability due to error accumulation at the level of DNA or erroneous checkpoint control of the cell cycle, as well as with mechanisms of DNA repair. Mechanisms of cellular transformation, metastasis, immune evasion and therapy resistance are also key lecture topics. The seminar talk will be about a current problem in the area of genomic instability or cell biology of tumors. In the lab of one of the contributing research groups, a relevant practical project will be done. |
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Learning and qualification objectives |
Consolidation of basic knowledge in the area of genomic instability and tumor development. Independent analysis of primary literature. Seminar talk concerning a chosen publication. Consolidation of knowledge concerning modern methods of gene analysis, DNA repair research and tumor biology. |
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Requirements for admission to module exam |
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Requirements for the award of credit points; exams (weighting of grades in %) |
Seminar presentation (30%) Written or oral exam (70%) Proof of participation in practical training (protocol) |