Dr. Mulla explaining Phage growth rates

NAVE workshop “Measuring Phage Parameters” in Utrecht

How do you estimate phage growth rates when you cannot measure viruses using optical density? Dr. Yuval Mulla introduces researchers to his PHORCE approach.
Dr. Mulla explaining Phage growth rates
Image: Tina Hauptfeld
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Published: | By: Tina Hauptfeld & Marcel Bäcker

On the last day of October, 30 researchers and students from six different countries joined the NAVE workshop, organized by the MGX group at Utrecht University. Led by Dr. Yuval Mulla from the VU Amsterdam, the participants learned how to measure phage activity in a sample, despite phages being much harder to observe than bacteria. During the hands-on part, the virus enthusiasts learned how to model the dynamics of bacterial populations undergoing phage predation and how to extract phage amplification rates from bacterial growth curves. Details of the method can be found in Yuval’s manuscript: Extreme diversity of phage amplification rates and phage-antibiotic interactions revealed by PHORCEExternal link.


In the afternoon, the participants engaged in a “research mixer”: inspired by science speed-dating events, selected speakers each had their own breakout-rooms/desks, where small groups stimulated lively discussions between in-person and online participants, and overlaps or potential collaborations could be discussed. Based on the key themes of the speakers’ presentations, the organizers built a research network, showing the overlaps between the projects. This gave the participants an additional tool to determine where they would fall within the network and who would be their most likely collaborators.


After many insightful scientific discussions, the participants’ gut microbiomes demanded nutrients! So, the day ended at a vegetarian pizza bar in Utrecht.

  • Dr. Mulla explaining Phage growth rates
    Dr. Mulla explaining Phage growth rates
    Image: Tina Hauptfeld
  • Discussions between in-person and online participants during the research mixer
    Discussions between in-person and online participants during the research mixer
    Image: Tina Hauptfeld
  • Discussions between in-person and online participants during the research mixer
    Discussions between in-person and online participants during the research mixer
    Image: Tina Hauptfeld
  • Research network of speakers based on key presentation themes
    Research network of speakers based on key presentation themes
    Image: Tina Hauptfeld